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human hepatoma cell line huh-7 bearing the hcv genotype 1b replicon  (Idenix Inc)

 
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    Idenix Inc human hepatoma cell line huh-7 bearing the hcv genotype 1b replicon
    Human Hepatoma Cell Line Huh 7 Bearing The Hcv Genotype 1b Replicon, supplied by Idenix Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+hepatoma+cell+line+huh-7+bearing+the+hcv+genotype+1b+replicon/human+hepatoma+cell+line+huh+7+bearing+the+hcv+genotype+1b+replicon/pm26479028-454-8-26
    Average 90 stars, based on 1 article reviews
    human hepatoma cell line huh-7 bearing the hcv genotype 1b replicon - by Bioz Stars, 2026-09
    90/100 stars

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    Article Title: Quinoline tricyclic derivatives. Design, synthesis and evaluation of the antiviral activity of three new classes of RNA-dependent RNA polymerase inhibitors.
    Article Snippet: In this study three new classes of linear N-tricyclic compounds, derived by condensation of the quinoline nucleus with 1,2,3-triazole, imidazole or pyrazine, were synthesized, obtaining triazolo[4,5-g]quinolines, imidazo[4,5-g]quinolines and pyrido[2,3-g]quinoxalines, respectively.. Title compounds were tested in cell-based assays for cytotoxicity and antiviral activity against RNA viruses representative of the three genera of the Flaviviridae family, that is BVDV (Pestivirus), YFV (Flavivirus) and HCV (Hepacivirus).. Quinoline derivatives were also tested against representatives of other RNA virus families containing single-stranded, either positive-sense (ssRNA) or negative-sense (RNA ), and double-stranded genomes (dsRNA), as well as against representatives of two DNA virus families.

    Article Title: Synthesis, cytotoxicity and antiviral evaluation of new series of imidazo[4,5-g]quinoline and pyrido[2,3-g]quinoxalinone derivatives.
    Article Snippet: A human hepatoma cell line (Huh-7) bearing the HCV genotype 1b replicon (GS4.1 cells), kindly provided by C. Seeger (Fox Chase University, Philadelphia, PA, USA) through Idenix Pharmaceuticals, was grown in D-MEM supplemented with 10% FBS, 2 mM L-glutamine, 110 mg/L sodium pyruvate, 0.1 mM non-essential amino acids, 100 U/mL penicillin, 100 μg/mL streptomycin and 0.5 mg/mL G418 (Invitrogen).



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    Idenix Inc human hepatoma cell line huh-7 bearing the hcv genotype 1b replicon
    Human Hepatoma Cell Line Huh 7 Bearing The Hcv Genotype 1b Replicon, supplied by Idenix Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+hepatoma+cell+line+huh-7+bearing+the+hcv+genotype+1b+replicon/human+hepatoma+cell+line+huh+7+bearing+the+hcv+genotype+1b+replicon/pm26479028-454-8-26
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    human hepatoma cell line huh-7 bearing the hcv genotype 1b replicon - by Bioz Stars, 2026-09
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    Idenix Inc human hepatoma cell line huh-7 bearing the hcv genotype 1b replicon gs4.1 cells
    Human Hepatoma Cell Line Huh 7 Bearing The Hcv Genotype 1b Replicon Gs4.1 Cells, supplied by Idenix Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+hepatoma+cell+line+huh-7+bearing+the+hcv+genotype+1b+replicon/human+hepatoma+cell+line+huh+7+bearing+the+hcv+genotype+1b+replicon/pm22513121-367-8-26
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